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Wednesday, June 4, 2025

Higher Copper Intake Associated with Reduced Risk of Late AMD


Copper depletion can trigger apoptosis of RPE and retinal cells, contributing to mechanisms of AMD.


Copper, found in foods typical of the Mediterranean diet, plays a critical role in various biological processes, including antioxidant defense and extracellular matrix biosynthesis. In a recent study, researchers investigated the relationship between the intake of copper, as well as iron, zinc, selenium in diet and late AMD, and found that out of all of these elements, increased copper consumption is associated with a reduced risk of late AMD, especially in those between the ages of 70 and 85.

The Age-Related Eye Disease Study (AREDS) 1 and AREDS 2 study demonstrated similar results, indicating that copper consumption was linked to reduced late-stage AMD risk.

The authors suggest that more research into the mechanism linking copper and late AMD development is warranted.

Thursday, May 29, 2025

Tryptyr - New Dry Eye Medication from Alcon


Alcon says its newest dry eye drug can show improved tear production as early as day 1 of therapy, overcoming a key complaint about some interventions that require a ramp-up period.

Tryptyr (pronounced trip-tir), released by Alcon activates trigeminal nerve signaling, leading to increased basal tear production. The recommended dosing of Tryptyr is twice per day. 

Roughly half of subjects receiving the test drug met the primary outcome of at least a 10mm increase in Schirmer score at day 14, up to a fourfold increase over controls treated with the vehicle only, 

The Alcon press release also states that some subjects treated with Tryptyr demonstrated statistically significant natural tear production as early as day 1. The company anticipates a US launch in the third quarter of 2025. Tryptyr will be supplied in preservative-free, single-use vials.

Thursday, May 22, 2025




 

Tuesday, February 27, 2024

ASTEROID HYALOSIS


This patient below has 20/20 vision in the right eye and 20/25 in the left. He does report seeing some "spots and lines", but they don't bother him. 


 

Monday, August 14, 2023

BERGMEISTER'S PAPILLAE

 


Bergmeister's Papillae is a fetal remnant of the hyaloid artery that extends from the optic nerve head to the developing lens of the eye.  Generally this vessel disintegrates entirely before birth, but in some cases, remnants remain. 

Friday, February 25, 2022

RETINOSCHISIS